Showing posts with label cancer. Show all posts
Showing posts with label cancer. Show all posts

Tuesday, 19 May 2015

The father of the high-fibre diet

Dr Denis Burkitt 1911-1993 is one of the unsung heroes of the healthy lifestyle.
He gave his name to Burkitt's lymphoma, a previously unknown facial cancer, which he observed in African children. It’s an unusual cancer because it’s linked to a virus. It came to the attention of Western doctors many years later, when cases started cropping up in patients whose immunity was compromised by AIDS.
His other claim to fame is at the other end of the medical spectrum - the importance of fibre in the diet. Before he published his book in 1979 there was little awareness of this. After its release there was a positive surge in the consumption of wholemeal bread, bran and muesli.
Dr Burkitt observed that Africans rarely suffered from constipation or - more significantly - diseases of the digestive system that were common in the West. He concluded that the African diet, which was very rich in fibre, prevented constipation and so helped to prevent many “diseases of civilisiation” including bowel cancer. 
He would have been fascinated in some recent research in which African-Americans swapped diets for just two weeks with some black South Africans. Several significant changes were observed in gut bacteria and molecules associated with colon cancer.
Don’t Forget Fibre in Your Diet, Denis Burkitt pub Martin Dunitz 1979
African diet swap http://bit.ly/1AcdC0J

Wednesday, 19 June 2013

The Value of Vitamins


It all started with the important discovery of vitamin deficiency diseases like scurvy, pellagra and rickets and now it's become a huge industry. You can hardly venture onto public transport without seeing adverts for supplements on railway stations, in tube trains or on the backs of buses. Anyone would think vitamins and minerals were to the body what oil is to the engine of a car - a simple top up and smooth running is assured.
It's very hard for the average consumer to make informed decisions in this area - the products sound tempting and "everyone's" taking them, so they must be good, mustn't they?
Doctors tend to be conservative on the subject - "you only need vitamins if you have a vitamin deficiency disease" would be their traditional position statement.
"Nutritionists" are far more liberal. They believe that vitamins not only prevent diseases but can also "heal" all manner of ills. They recommend a vitamin (or six) for every ailment. As if that extra oil in the car could mend a broken engine part. They tend to be overly eager to support their beliefs by citing  evidence from experiments involving cells and mice.
In the middle ground we have the lucrative supplement industry with a vested interest in convincing us that we need supplements and so getting us to part with our money.
So what's the scientific take on all this?
Evidence cannot convince the scientific community unless it involves a large group of humans (not genetically modified mice), taking vitamins over a long period of time, with a "blind" comparison group taking placebos. Only then can you check whether the supplements are safe and whether any positive effects result. Such trials are, of course, very expensive and are consequently rather rare. Such studies that do exist have sometimes shown no benefit, or even demonstrated harm to those who take vitamin supplements for long periods.
In summary - the better quality evidence has generally been "disappointing" inasmuch as it has failed to show that supplements reduce your chances of avoiding colds or cancers, or that they increase your chances of living longer. Vitamins cure vitamin deficiency diseases, but evidence that they are curative in other areas is very flimsy indeed.
The other problem for consumers is that vitamins are very lightly regulated. In Europe, now, you cannot even hint on packaging that a food has an active health benefit. There are only a few examples that are approved by the European Food Standards Agency (notably oats and the cholesterol-lowering products such as Benecol margarine). Food packaging is still allowed to bear words like "fortified with Vitamin A" or "a source of vitamin C" as long as they contain minimum amounts of the relevant nutrient.
Where food supplements are concerned, as long as they are not actually toxic or contaminated and as long as they make their claims in qualified terms such as "may help support a healthy immune system" they are very lightly regulated. In other words there is not a lot of consumer protection.
Cochrane systematic reviews are a good place to look if you want to check the best evidence about supplements. A new book has been published which goes into more myth-busting detail and it looks like interesting reading.